Physiological Effects Ketone Ester in Heart

Running, not enrolling · Not applicable · Has a placebo group

Conditions studied: Heart Failure

In brief

The study is aimed to phenotype with cardiac MRI the physiological effects of ketone esters on the heart. Patients with heart failure will be recruited and given ketone esters or placebo in a randomized fashion. Cardiac MRI will be performed at baseline and after 12weeks follow up.

Key facts

Study ID

NCT05924802

Run by

The Cleveland Clinic

People needed

50

Starts

2024-06-01

Expected to finish

2029-09-01

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• heart failure EF < 40%

You may not qualify if…

• Claustrophobia
• Contraindicated implanted device

Where it is running

• Cardiovascular Innovation Research Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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