Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering
Completed · Phase 1 · Has a placebo group
Conditions studied: Opioid Use Disorder
In brief
The aims of this study are to 1) explore the efficacy of hyperbaric oxygen therapy (HBOT) applied at two different pressures compared to sham treatment in relieving signs and symptoms (both physical and psychological) of opioid withdrawal in human subjects associated with methadone dose reductions; and 2): explore whether HBOT can increase the odds of successful methadone dose reduction in patients who are interested in tapering their opioid dose. The investigators aim to explore, through qualitative methods, individual's experiences with treatment for opioid use disorder (OUD).
Key facts
- Study ID
- NCT05924022
- Run by
- Washington State University
- People needed
- 25
- Starts
- 2023-12-04
- Expected to finish
- 2025-08-15
- Last updated by the study team
- 2026-06-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Enrollment in a supervised opioid treatment program at the Spokane Regional Health District
- Age greater than 18 years
- Ability to read, speak, and write English
- Ability to provide written informed consent.
You may not qualify if…
- Pregnancy
- Any other medical or psychiatric condition that the PI, Co-PI (physician of record) or the Spokane Hyperbaric Center medical director determine might compromise safe study participation in the HBOT clinic (including but not limited to active psychosis, history of frequent psychiatric hospitalizations, severe anxiety with claustrophobia, aggression)
- Upper respiratory infection
- Emphysema
- Air cysts in the lung
- History of thoracic or ear surgery
- Taking the medication Antabuse for alcohol addiction
- High fever.
Where it is running
- Spokane Regional Health District — Spokane, Washington, United States
Full record on ClinicalTrials.gov
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