Modulation of Brain Oscillations Underlying Working Memory

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Working Memory

In brief

This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory. tACS is a noninvasive method used to modulate the timing and patterns of brain rhythms via weak electric currents passed through electrodes on the scalp.

Key facts

Study ID

NCT05923606

Run by

Massachusetts General Hospital

People needed

32

Starts

2024-07-10

Expected to finish

2027-03-31

Last updated by the study team

2026-02-09

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Able to provide informed consent
• Fluent in English.

You may not qualify if…

• History of a neurological/psychiatric disorder
• Current use of psychotropic medications
• Current use of substances and drugs that were shown to affect tES (transcranial electrical stimulation) efficacy (dopamine altering drugs, nicotine, NMDA (N-methyl-D-aspartate) antagonists/agonists, sodium/calcium channel blockers, norepinephrine reuptake inhibitors, GABAergic modulators and selective serotonin reuptake inhibitors)
• Contraindications for tACS (e.g., history of seizures, metallic implants in the head or neck, implanted brain stimulators, vagus nerve stimulators, pacemakers, pregnancy)

Where it is running

• Martinos Center for Biomedical Imaging — Charlestown, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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