Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

Recruiting now

Conditions studied: Atrial Fibrillation, Functional Mitral Regurgitation, Functional Tricuspid Regurgitation

In brief

A prospective, observational cohort study designed to identify clinical phenotypes and evaluate predictors \& outcomes of functional mitral and tricuspid valve regurgitation in patients with atrial fibrillation. Participant will under go: * Baseline echocardiography * Cpex Echocardiography * Blood test: BNP * 1 year follow up Echocardiography Participants will be stratified into three subgroups: * Atrial Functional MR * Atrial Functional TR * Mixed MR \& TR

Key facts

Study ID

NCT05920824

Run by

Barts & The London NHS Trust

People needed

60

Starts

2023-08-23

Expected to finish

2027-08-01

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Informed consent
• Age of 18 years or older
• Atrial fibrillation
• Moderate or severe atrial valve disease
• Adequate 2D echocardiography views including parasternal long axis, short axis, apical two chamber, apical three chamber and four chamber.

You may not qualify if…

• Unwilling or unable to give consent
• Left ventricular impairment (ejection fraction < 50%).
• Primary/organic valve disease

Where it is running

• St Bartholomew's Hospital — London, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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