Automated Imaging Differentiation of Parkinsonism

Running, not enrolling

Conditions studied: Parkinson Disease, Multiple System Atrophy, Parkinson Variant, Progressive Supranuclear Palsy

In brief

The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis.

Key facts

Study ID

NCT05913687

Run by

University of Florida

People needed

315

Starts

2021-07-22

Expected to finish

2027-03-31

Last updated by the study team

2026-07-31

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Parkinson's disease diagnosis within 5-9 years of baseline date
• MSAp diagnosis
• PSP diagnosis

You may not qualify if…

• metal implants in the body that preclude an MRI (pacemaker, metallic clip, neurostimulator, etc)
• claustrophobia
• pregnancy

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of California San Diego — La Jolla, California, United States
• University of California San Francisco — San Francisco, California, United States
• University of Florida — Gainesville, Florida, United States
• University of South Florida — Tampa, Florida, United States
• Augusta University — Augusta, Georgia, United States
• Northwestern University — Chicago, Illinois, United States
• University of Chicago — Chicago, Illinois, United States
• University of Kentucky — Lexington, Kentucky, United States
• Johns Hopkins University — Lutherville, Maryland, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Massachusetts General Hospital — Charlestown, Massachusetts, United States
• University of Michigan — Ann Arbor, Michigan, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Washington University in St. Louis — St Louis, Missouri, United States
• Albany Medical College — Albany, New York, United States
• Duke University Medical Center — Durham, North Carolina, United States
• Wake Forest University — Winston-Salem, North Carolina, United States
• Pennsylvania State University — Hershey, Pennsylvania, United States
• Ottawa Hospital Research Institute — Ottawa, Canada
• Centre for Addiction and Mental Health — Toronto, Canada

Full record on ClinicalTrials.gov

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