Adapting a Behavioral Intervention to Accommodate Cognitive Dysfunction in People Who Inject Drugs

Completed · Not applicable

Conditions studied: Cognitive Dysfunction

In brief

The goal of this pilot work was to determine if the cognitive dysfunction accommodation strategies help patients retain/utilize more HIV prevention information and increase PrEP adherence. Fifty people who inject drugs (PWID) were prescribed PrEP and randomized to one of two conditions, Twenty-five PWID participated in a standard HIV prevention session and 25 other PWID participated in a HIV prevention session with the included accommodation strategies. At recruitment participants were asked to provide self-report of the screening form and cognitive functioning. The intervention consisted of a total of 5 sessions: 1 meeting to gain baseline information of participants and 4 intervention sessions. Participants completed the consent form, demographics, skills assessment, drug use behavior assessment, and HIV risk behavior assessment at the pre-interview meeting. Participants completed PrEP uptake assessments and skills assessments immediately following the intervention to compare the pre/post results between the two groups. All participants also completed an acceptability rating to help researchers determine the acceptability of the accommodation strategies used, at the end of the 4th session. The objective was to determine if the proposed accommodation strategies are feasible and efficacious at improving HIV prevention outcomes, including knowledge and skills. Information gleaned from this process will be used to refine the intervention approach for future testing and implementation.

Key facts

Study ID

NCT05912374

Run by

University of Connecticut

People needed

50

Starts

2022-09-07

Expected to finish

2022-12-12

Last updated by the study team

2023-06-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• at least 18 years or older
• reported injection drug use in the past 30 days
• reported engagement in drug- and/or sex- related HIV risk behaviors
• HIV negative
• are willing to initiate PrEP use
• can communicate (read, write and speak) in English
• experience mild/moderate level of cognitive dysfunction

You may not qualify if…

• cannot attend all study sessions
• actively homicidal and/or suicidal

Where it is running

• APT Foundation — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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