The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
Recruiting now · Not applicable
Conditions studied: Insulin Resistance, Impaired Glucose Tolerance, Obesity, Metabolic Disturbance
In brief
This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women? 3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?
Key facts
- Study ID
- NCT05912348
- Run by
- University of New Hampshire
- People needed
- 45
- Starts
- 2023-02-08
- Expected to finish
- 2026-09-30
- Last updated by the study team
- 2024-07-17
Who can join
Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18-30 years of age
- Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (>2 days/week).
- Fair cardiorespiratory fitness levels (Men: VO2>38.4 ml/kg/min; Women: VO2>32.6 ml/kg/min).
You may not qualify if…
- Hypertension (resting or diagnosed)
- Impaired fasting blood glucose (>100mg/dL)
- Diagnosed cardiovascular disease
- Diagnosed diabetes
- Diagnosed cancer
- Diagnosed chronic kidney disease
- Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.
Where it is running
- University of New Hampshire Cardiometabolic Research Laboratory — Durham, New Hampshire, United States (enrolling)
Full record on ClinicalTrials.gov
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