European Study of Prodromal iNPH

Recruiting now

Conditions studied: Normal Pressure Hydrocephalus, Hydrocephalus

In brief

To investigate if progression from prodromal into symptomatic NPH can be predicted from advanced neuroimaging, biomarkers in cerebrospinal fluid (CSF) and plasma and investigate the unknown mechanisms causing deterioration by investigating longitudinal changes in the above-mentioned variables. Three different cohorts with both asymptomatic and symptomatic patients as well as healthy controls will be investigated over time, both without intervention and before and after shunt surgery.

Key facts

Study ID

NCT05910944

Run by

Johan Virhammar

People needed

140

Starts

2023-11-01

Expected to finish

2035-12-31

Last updated by the study team

2026-04-30

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

Where it is running

• Bellaria Hospital — Bologna, Italy (enrolling)
• Uppsala University Hospital — Uppsala, Sweden (enrolling)
• Kuopio University Hospital — Kuopio, Finland
• Karolinska University Hospital — Stockholm, Sweden
• Umeå University Hospital — Umeå, Sweden
• Linköping University Hospital — Linköping, Sweden
• Sahlgrenska University Hospital — Gothenburg, Sweden

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.