Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Recruiting now · Phase 2

Conditions studied: Heart Transplantation, Acute Kidney Injury

In brief

The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.

Key facts

Study ID

NCT05909150

Run by

Fernando Bacal

People needed

74

Starts

2023-11-08

Expected to finish

2027-03-01

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Hospitalized patients submitted to orthotopic heart transplantation (HT)

You may not qualify if…

• Requirement of renal replacement therapy at the time of HT
• Requirement of extracorporeal membrane oxygenation (ECMO) before or immediately after HT
• Severe peri-operative mechanical complications
• Double transplant (e.g. heart-kidney or heart-lung)
• Hypernatremia (Na ≥ 145)
• Severe hyponatremia (Na ≤ 120)

Where it is running

• Heart Institute, University of São Paulo. — São Paulo, Brazil (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.