Early Detection & Intervention of Cerebral Palsy in Ireland

Recruiting now

Conditions studied: Cerebral Palsy, Neurodevelopmental Disorders

In brief

Cerebral palsy (CP) is the most common lifelong physical disability. It is defined as a non-progressive disorder of movement originating from neural lesions in the perinatal period, and is associated with a wide range of common comorbidities in many individuals. These include problems speaking, hearing, seeing, thinking, feeding and controlling their bladder. People with CP often have additional challenges such as behavioural and emotional issues, pain, and poor sleep. Many of these challenges respond well to intervention in early childhood, as brain plasticity is at its greatest in the first 2 years of life. However, in most clinical settings, the age for diagnosis of CP is between 24 to 29 months, after this window of neurodevelopmental opportunity. This project will aim to improve the Early Detection of Cerebral Palsy in Ireland. This will be achieved by implementing an evidence-based approach to follow-up of High risk infants.

Key facts

Study ID

NCT05907837

Run by

University College Cork

People needed

1500

Starts

2023-07-01

Expected to finish

2028-06-30

Last updated by the study team

2023-10-02

Who can join

Age: any, up to 1. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Legal guardians must be able and willing to give written informed consent and to comply with the requirements of this study protocol.
• All infants considered high risk for cerebral palsy and neuro-developmental impairment will be eligible, specifically including:
• All preterm infants born ≤32 weeks Post Menstrual Age or ≤1500 gm birth weight
• All encephalopathic infants
• Neurological risk factors (e.g., injury/malformation on neuroimaging, persistently abnormal neurological exam)

You may not qualify if…

• Death prior to discharge from the neonatal unit.

Where it is running

• Cork University Maternity Hospital — Cork, Ireland (enrolling)
• Coombe Women and Infants University Hospital — Dublin, Ireland (enrolling)
• National Maternity Hospital — Dublin, Ireland (enrolling)
• The Rotunda Hospital — Dublin, Ireland (enrolling)
• University Maternity Hospital Limerick — Limerick, Ireland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.