A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Recruiting now · Phase 1/Phase 2
Conditions studied: Advanced Solid Tumor, High Grade Serous Adenocarcinoma of Ovary, Squamous Non-small-cell Lung Cancer, Triple Negative Breast Cancer, Head and Neck Squamous Cell Carcinoma, Ovarian Carcinosarcoma, Uterine Carcinosarcoma, Uterine Serous Carcinoma, Endometrium Cancer, Chromosomal Instability
In brief
This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.
Key facts
- Study ID
- NCT05902988
- Run by
- Volastra Therapeutics, Inc.
- People needed
- 200
- Starts
- 2023-10-18
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-11-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Froedtert & the Medical College of Wisconsin — Milwaukee, Wisconsin, United States (enrolling)
- Hoag Memorial Hospital — Newport Beach, California, United States (enrolling)
- University of Colorado Cancer Center — Aurora, Colorado, United States (enrolling)
- Yale Cancer Center — New Haven, Connecticut, United States (enrolling)
- Kellogg Cancer Center — Evanston, Illinois, United States (enrolling)
- Community Health Network — Indianapolis, Indiana, United States (enrolling)
- Johns Hopkins Sidney Kimmel Comprehensive Cancer Center — Baltimore, Maryland, United States (enrolling)
- University of Michigan — Ann Arbor, Michigan, United States (enrolling)
- University of Southern California — Los Angeles, California, United States (enrolling)
- Memorial Sloan Kettering Cancer Center — New York, New York, United States (enrolling)
- The Christ Hospital — Cincinnati, Ohio, United States (enrolling)
- Women & Infants Hospital — Providence, Rhode Island, United States (enrolling)
- M.D. Anderson Cancer Center — Houston, Texas, United States (enrolling)
- START Midwest — Grand Rapids, Michigan, United States
Full record on ClinicalTrials.gov
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