Yoga for Treatment of Overactive Bladder in Pediatric Patients

Recruiting now · Not applicable

Conditions studied: Overactive Bladder, Overactive Bladder Syndrome, Overactive Detrusor

In brief

The goal of this pilot study is to assess the impact of yoga as a treatment modality in pediatric patients age 8-18 diagnosed with idiopathic overactive bladder as measured by validated questionnaires and urinary biomarkers. The main question it aims to answer is: Does yoga help improve overactive bladder symptoms in this patient population? Participants will take part in a weekly yoga session for a total of 6 weeks with validated questionnaires and urinary samples for biomarkers to be completed at the beginning, middle and end of the study. This study will follow a cross-over study design and patients will receive standard of care while not in the active treatment arm.

Key facts

Study ID

NCT05895045

Run by

Duke University

People needed

40

Starts

2026-01-01

Expected to finish

2026-12-31

Last updated by the study team

2026-01-30

Who can join

Age: 8 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 8-18 years of age
• History of non-neurogenic overactive bladder or detrusor overactivity and/or urinary incontinence (ICD 10 codes respectively - N32.81, N39.498)
• Obtained legally effective informed consent and Health Insurance Portability and Accountability Act (HIPPA) authorization from the participant or the participant's parent/legal guardian
• Minor participant is willing and able to provide assent (as applicable)
• Vancouver Dysfunctional Elimination Syndrome[15] score of ≥11 and a positive modified bother score within 30 days of consent

You may not qualify if…

• Known or apparent untreated anatomical abnormality of lower urinary tract (i.e. untreated ureterocele)
• Known neurogenic bladder (e.g., spina bifida, history of spinal cord injury, tethered cord)
• Nerve damage that may impact pelvic floor function
• History of chemodenervation of the bladder (e.g., via intravesical instillation or intradetrusor injection of botulinum toxin)
• Active, untreated UTI at the time of enrollment (UTI undergoing active treatment is allowable)
• Current or previous pregnancy at screening or planned pregnancy during the duration of the study, for females of childbearing potential
• Any condition that, in the judgment of the investigator or treating clinician, precludes participation because it could affect participant safety

Where it is running

• Duke University Hospital — Durham, North Carolina, United States (enrolling)

Full record on ClinicalTrials.gov

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