Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy

Recruiting now · Not applicable

Conditions studied: Cardiac Surgery

In brief

Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%. Exact pathogenetic mechanisms for developing chronic pain after sternotomy are unknown. Apart from intraoperative nerve damage and subsequent postoperative neuropathic pain, operation techniques, age, sex, pre-existing pain, genetic and psychosocial factors, severe postoperative pain, and analgesic management are suspected to have an impact on the development of PSPS .

Key facts

Study ID

NCT05885230

Run by

Beni-Suef University

People needed

138

Starts

2023-05-01

Expected to finish

2027-05-01

Last updated by the study team

2026-06-23

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age between 18 and 75 years.
• patient scheduled to undergo elective on-pump cardiac surgery with sternotomy.
• American Society of Anesthesiologists classification of physical status < IV.

You may not qualify if…

• emergency surgery.
• off-pump surgery.
• redo surgery.
• ejection fraction less than 35%.
• refusal of the patient.
• known hypersensitivity to LA.
• chronic opioid use or chronic pain patient.
• psychiatric problems or communication difficulties.
• liver insufficiency (defined as a serum bilirubin ≥ 34 μmol/l, albumin ≤ 35 g/dl, INR ≥ 1.7).
• renal insufficiency (defined as a glomerular filtration rate < 44 ml/min).
• obstructive sleep apnea syndrom.
• coexisting hematologic disorders.
• pregnancy or breastfeeding.

Where it is running

• Benisuef University Hospital — Banī Suwayf, e\EYGPT, Egypt (enrolling)

Full record on ClinicalTrials.gov

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