Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

Status unconfirmed · Not applicable · Has a placebo group

Conditions studied: Photoaging

In brief

This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.

Key facts

Study ID

NCT05882084

Run by

Integrative Skin Science and Research

People needed

24

Starts

2023-07-24

Expected to finish

2023-12-31

Last updated by the study team

2023-07-25

Who can join

Age: 30 and older, up to 55. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Females who are 30 to 55 years of age
• Half of the women will have Fitzpatrick skin type 1-3 and the other half of the women will have Fitzpatrick skin type 4-6

You may not qualify if…

• Individuals with a known allergy to astaxanthin or other carotenoids (such as zeaxanthin, lutein, lycopene).
• Individuals who are unwilling to discontinue carotenoid supplementation for at least 1 month prior to enrollment
• Individuals unwilling to restrict intake of foods like shrimp, salmon, mangos, carrots, and tomatoes during the study.
• New supplementation within 4 weeks with tocopherol
• Individuals who are unwilling to stay consistent with a facial cleansing regimen.
• Those who are unwilling to discontinue topical hydroquinone, retinoid or benzoyl peroxide for 2 weeks prior to enrollment
• Individuals who are pregnant or breastfeeding.
• Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
• Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years

Where it is running

• Integrative Skin Science and Research — Sacramento, California, United States (enrolling)

Full record on ClinicalTrials.gov

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