A Switch Study From High-Sodium Oxybate to Xywav to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Completed · Phase 4
Conditions studied: Narcolepsy
In brief
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to Xywav, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Key facts
- Study ID
- NCT05869773
- Run by
- Jazz Pharmaceuticals
- People needed
- 155
- Starts
- 2023-06-26
- Expected to finish
- 2025-03-10
- Last updated by the study team
- 2026-04-24
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Ohio Sleep Medicine and Neuroscience — Dublin, Ohio, United States
- OHSU Hospital — Portland, Oregon, United States
- Abington Neurological Associates, LTD — Abington, Pennsylvania, United States
- University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States
- Science 37 — Culver City, California, United States
- M3 Wake Research — Encino, California, United States
- So Cal Clinical Research — Huntington Beach, California, United States
- Long Beach Research Institute — Lakewood, California, United States
- Stanford School of Medicine — Redwood City, California, United States
- TriValley Sleep Center — San Ramon, California, United States
- SDS Clinical Trials, Inc. — Santa Ana, California, United States
- FWD Clinical Research — Boca Raton, Florida, United States
- Meris Clinical Research, LLC — Brandon, Florida, United States
- Ocean Wellness Center — Miami, Florida, United States
- Serenity Research Center LLC — Miami, Florida, United States
- Florida Pediatric Research Institute, LLC — Orlando, Florida, United States
- Sleep Practitioners, LLC — Macon, Georgia, United States
- Saltzer Medical Group — Nampa, Idaho, United States
- University of Louisville — Louisville, Kentucky, United States
- University of Maryland Medical Center — Baltimore, Maryland, United States
- Neurocare, Inc — Newton, Massachusetts, United States
- Sparrow Health System — Lansing, Michigan, United States
- Bryan Medical Center — Lincoln, Nebraska, United States
- Henderson Clinical Trials LLC — Henderson, Nevada, United States
- Advanced Respiratory and Sleep Medicine, PLLC — Huntersville, North Carolina, United States
Full record on ClinicalTrials.gov
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