Study on the Mechanism of Eating Disorder
Recruiting now
Conditions studied: Anorexia Nervosa, Bulimia Nervosa
In brief
Eating disorders (EDs) are severe chronic psychiatric disorders with a not fully understood etiopathogenesis. Previous studies have revealed some biological mechanisms of EDs. However, the etiology and maintenance mechanism of EDs, especially the neuro-mechanisms is still unknown. To explore the pathogenic mechanism and treatment biomarkers of EDs, we design this study. the multidimensional data including the clinicopathological features, neuroimaging data (functional and structural magnetic resonance imaging), electroencephalogram and inflammatory cytokines will be used to investigate the biomarkers for diagnosis and treatment effectiveness.
Key facts
- Study ID
- NCT05862389
- Run by
- Peking University
- People needed
- 750
- Starts
- 2022-09-01
- Expected to finish
- 2030-12-01
- Last updated by the study team
- 2023-05-24
Who can join
Age: 13 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Anorexia nervosa
- Anorexia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5);
- Age: 13-35 (including 13 and 35)
- BMI: 13-17.5kg/m\^2
- The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol.
- Do not take any psychiatric medications in past one month.
- Bulimia nervosa
- Bulimia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5);
- Age: 13-35 years old (including 13 and 35)
- The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol.
- Do not take any psychiatric medications in past one month.
You may not qualify if…
- Patients who meet DSM-5 diagnostic criteria for other mental disorders: Major depressive disorder, anxiety, obsessive-compulsive disorder, personality disorder, mental retardation; drug and/or alcohol dependence;
- Patients who receive repetitive Transcranial Magnetic Stimulation (rTMS) or modified electroconvulsive therapy (MECT) treatment in past six months.
- Patients with severe suicidal tendencies or suicidal behavior
- Pregnant or lactating women;
- Patients with MRI contraindications;
- Patients who are regarded as unsuitable by investigators for this clinical trial.
Where it is running
- Institute of Mental Health, Peking University Sixth Hospital — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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