Breathing Training and Exercise Capacity in Non-CFB

Recruiting now · Not applicable

Conditions studied: Non-cystic Fibrosis Bronchiectasis

In brief

The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing muscles, and general clinical status in people with non-cystic fibrosis bronchiectasis (non-CFB).

Key facts

Study ID

NCT05860803

Run by

Mayo Clinic

People needed

50

Starts

2024-01-15

Expected to finish

2026-12-01

Last updated by the study team

2026-01-06

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks.
• Able and willing to provide informed consent to participate in the study.

You may not qualify if…

• Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise.
• Presence of advanced heart failure.
• Current use of antibiotics.
• Acute exacerbation(s) within 3-weeks prior to study commencement.
• Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.

Where it is running

• Mayo Clinic Florida — Jacksonville, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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