Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
Recruiting now · Phase 4 · Has a placebo group
Conditions studied: Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency
In brief
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce the risk of subsequent peritoneal dialysis-related peritonitis.
Key facts
- Study ID
- NCT05860270
- Run by
- Peking University First Hospital
- People needed
- 176
- Starts
- 2023-06-15
- Expected to finish
- 2026-05-31
- Last updated by the study team
- 2024-08-06
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Medically stable and receiving peritoneal dialysis for > 1 month
- Older than 18 years old
- Serum 25(OH)D < 30ng/ml
- Adequate dialysis on evaluation with weekly Kt/V ≥ 1.5, or (revised time: 2023-7-11) without clinical uremic symptoms
You may not qualify if…
- Receive Vitamin D2/D3 during the previous 1 month (revised time: 2023-7-11) ;
- History of allergic reaction to Cholecalciferol;
- Current or past malignant disease, active hepatitis or hepatic failure, active autoimmune disease, severe digestive malabsorption or an eating disorder, HIV/AIDS;
- Acute systemic infection, cardiovascular disease, surgery, or trauma in the last month;
- A high probability of receiving a kidney transplant or transferring to hemodialysis or drop-out due to socioeconomic causes within 6 months;
- History of kidney transplant;
- Hemodialysis combined with peritoneal dialysis currently;
- Pregnant or breastfeeding;
- Not suitable enrolled assessed by researchers, including patients who could not regular follow-up
Where it is running
- Peking University First Hospital — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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