PRECISION-TBI - An Observational Study of Patients With Moderate to Severe Traumatic Brain Injury
Recruiting now
Conditions studied: Trauma, Brain
In brief
Traumatic Brain Injury (TBI) is a devastating condition and a leading cause of long-term disability. Every patient with TBI has a different type of injury and is treated differently from hospital to hospital making it very difficult to identify the most effective treatments. The current study focuses on the most severe types of TBI that require hospital ICU care - moderate to severe TBI (m-sTBI). The overall aim of this study is to collect data about how different hospitals manage m-sTBI in Australia, and to quantify the variability that likely exists. Recovery at 6 months post-injury will be collected to allow a better understanding on how different injuries and treatments affect long term outcomes.
Key facts
- Study ID
- NCT05855252
- Run by
- Australian and New Zealand Intensive Care Research Centre
- People needed
- 300
- Starts
- 2022-08-14
- Expected to finish
- 2025-07-01
- Last updated by the study team
- 2024-08-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years
- Clinical diagnosis of moderate to severe TBI
- Insertion of invasive intra-cranial monitoring
- Study inclusion within 48 hours of ICU admission
You may not qualify if…
- Admission to the ICU is solely for the purposes of palliative care or confirmation of organ donation
- Advanced care directive or previously stated wish not to be included in research activities
Where it is running
- St George Hospital — Kogarah, New South Wales, Australia (enrolling)
- John Hunter Hospital — New Lambton Heights, New South Wales, Australia (enrolling)
- Royal North Shore Hospital — St Leonards, New South Wales, Australia (enrolling)
- Westmead Hospital — Westmead, New South Wales, Australia (enrolling)
- Royal Brisbane and Women's Hospital — Herston, Queensland, Australia (enrolling)
- Royal Adelaide Hospital — Adelaide, South Australia, Australia (enrolling)
- Flinders Medical Centre — Bedford Park, South Australia, Australia (enrolling)
- The Alfred Hospital — Melbourne, Victoria, Australia (enrolling)
- Royal Melbourne Hospital — Melbourne, Victoria, Australia (enrolling)
Full record on ClinicalTrials.gov
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