Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

Recruiting now

Conditions studied: Opioid-Induced Esophageal Dysfunction

In brief

The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).

Key facts

Study ID

NCT05854303

Run by

Mayo Clinic

People needed

26

Starts

2023-09-18

Expected to finish

2026-11-01

Last updated by the study team

2025-10-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients enrolled in the Pain Rehabilitation Center for opioid cessation, with or without esophageal symptoms.

You may not qualify if…

• Inability to provide informed consent.
• Patients with previous gastroesophageal surgery or pneumatic dilation.
• Esophageal botulinum toxin injection within the prior 12 months.
• Esophageal stricture
• Achalasia types I and II
• Allergy to Lidocaine or other local anesthetics
• Subjects on anticoagulation
• Bilateral nasal obstruction
• Pregnancy or breast feeding

Where it is running

• Mayo Clinic Minnesota — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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