The Proactive Ophthalmic Examination Cohort
Recruiting now
Conditions studied: Vision Impairment, Eye Diseases
In brief
The Proactive Ophthalmic Examination Cohort of Older Adults is a prospective cohort study recruiting community-dwelling older adults aged 65 years or older. Through comprehensive assessment of demographic profiles, medical histories, and ocular structural and functional parameters, alongside systematic collection of ophthalmic and systemic clinical data and biological specimens, we will establish a multidimensional, high-quality ocular health database encompassing demographic characteristics, socioeconomic factors, lifestyle variables, ocular disease risk factors, subjective ocular symptoms, objective examination findings, and biospecimens. The study will investigate the onset and progression patterns of ocular diseases, associated risk factors, and mechanisms of ocular aging in older populations, while simultaneously providing normal-controlled clinical and genomic data for other clinical studies on eye diseases. Furthermore, leveraging algorithmic innovation and artificial intelligence technologies, we will develop a personalized risk prediction and monitoring platform for age-related eye diseases, enhancing early screening and diagnostic capabilities and advancing precision medicine for ocular health in older adults.
Key facts
- Study ID
- NCT05851287
- Run by
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- People needed
- 5000
- Starts
- 2023-02-20
- Expected to finish
- 2034-02-19
- Last updated by the study team
- 2026-06-09
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged 65 years or older
You may not qualify if…
- Unable to complete required systemic or ophthalmic examinations due to frailty, poor general health, or other physical limitations
- Refusal to participate in the study
Where it is running
- Zhongshan Ophthalmic Center, Sun Yat-sen University — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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