Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Recruiting now · Not applicable
Conditions studied: Aphasia, Stroke
In brief
The investigators propose a pilot crossover trial of 2 behavioral language treatments, with randomized order of treatments and blinded assessors, to determine if a therapy designed to stimulate right hemisphere functions (Producing Increasingly Complex Themes Using Right-hemisphere Engagement Implemented with Telemedicine - PICTURE IT; described below) is more effective in improving discourse than a published computer delivered lexical treatment (shown previously to improve naming) in subacute post-stroke aphasia.
Key facts
- Study ID
- NCT05845047
- Run by
- Johns Hopkins University
- People needed
- 70
- Starts
- 2023-05-31
- Expected to finish
- 2031-10-01
- Last updated by the study team
- 2025-09-23
Who can join
Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 or older
- Premorbid proficiency in English
- Left hemisphere ischemic or hemorrhagic stroke confirmed by imaging, which occurred either 1-4 months or ≥ 6 months ago
- Diagnosis of aphasia secondary to stroke as defined using the Western Aphasia Battery-Revised Aphasia Quotient < 93.8.
- Capable of giving informed consent or indicating another to provide informed consent
You may not qualify if…
- Prior history of neurologic disease affecting the brain (e.g., brain tumor, multiple sclerosis, traumatic brain injury) other than stroke
- Prior history of severe psychiatric illness, developmental disorders or intellectual disability (e.g., PTSD, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders)
- Inability to follow the treatment procedure as indicated by appropriate (not necessarily accurate) engagement during 5 probes of each.
- Uncorrected severe visual loss or hearing loss by self-report and medical records
Where it is running
- Johns Hopkins School of Medicine — Baltimore, Maryland, United States (enrolling)
Full record on ClinicalTrials.gov
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