Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

Recruiting now

Conditions studied: OCD

In brief

This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.

Key facts

Study ID

NCT05843604

Run by

Centre Hospitalier Henri Laborit

People needed

100

Starts

2023-07-03

Expected to finish

2027-09-01

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions)
• Understand and accept the constraints of the study
• Be a beneficiary or affiliated to a Health Insurance scheme

You may not qualify if…

• Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998)
• Generalized anxiety disorder, social anxiety, nicotine dependence and history of a major depressive episode are not exclusion criteria according to the M.I.N.I. version 5.0 (Sheehan et al., 1998)
• Have a serious intercurrent pathology
• Being a pregnant woman
• Being a woman of childbearing age without effective contraception.
• Being hospitalized under duress or on an outpatient basis in a care program
• Being under judicial protection (reinforced curatorship, guardianship)

Where it is running

• Centre Hospitalier Henri Laborit — Poitiers, France (enrolling)

Full record on ClinicalTrials.gov

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