Chronic Thromboembolic Disease Registry
Recruiting now
Conditions studied: Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Disease
In brief
The goal of this patient registry is to learn about the natural history in patients with chronic thromboembolic disease (CTD) and/or chronic thromboembolic pulmonary hypertension (CTEPH). The main question\[s\] it aims to answer are: * Long-term outcome after various types of treatment, including medication, balloon pulmonary angioplasty, and pulmonary endarterectomy * Effect of treatment on patient's quality of life and exercise tolerance Participants will be followed longitudinally to assess their health outcomes and quality of life via chart review and health quality surveys.
Key facts
- Study ID
- NCT05843500
- Run by
- University of California, San Francisco
- People needed
- 100
- Starts
- 2023-08-01
- Expected to finish
- 2028-07-01
- Last updated by the study team
- 2026-07-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients referred with CTED and/or CTEPH defined as:
- Mean pulmonary arterial pressure (mPAP) > 20 mmHg at rest with pulmonary vascular resistance (PVR) > 2 Wood units (WU); or if mPAP ≤ 20 mmHg or PVR ≤ 2 WU at rest, have exercise limitations from chronic thromboembolic pulmonary disease (CTEPD) without pulmonary hypertension (PH)
- Radiologic finding of chronic thromboembolic disease, including abnormal ventilation perfusion scan, pulmonary angiogram, computer tomographic pulmonary angiogram, or magnetic resonance pulmonary angiogram
- Post-embolic exercise intolerance and evidence of chronic thromboembolic disease in the absence of resting pulmonary hypertension
- Treatment with anticoagulation for ≥ 3 months before diagnosis of CTEPH or CTEPD without PH
- Age ≥ 18 years
You may not qualify if…
- Main cause of PH other than World Health Organization (WHO) group 4 (CTEPH)
- Patient's refusal to participate in clinical research and/or receive intervention
Where it is running
- University of California San Francisco — San Francisco, California, United States (enrolling)
Full record on ClinicalTrials.gov
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