Clinical Value of ETCOc in the Diagnosis and Treatment of ABO-HDN
Recruiting now
Conditions studied: ABO Hemolytic Disease of Newborn
In brief
A prospective observational cohort study was designed. 1. Comparing of the clinical indicators between the hemolytic group and the non-hemolytic group,such as End-tidal carbon monoxide corrected for ambient CO(ETCOc),direct antiglobulin test(DAT), the highest total serum bilirubin level and hemoglobin. To explore the role of ETCOc in the diagnosis of neonatal ABO hemolytic disease. 2. Comparing of the clinical indicators between the neonates with IVIG treatment and the neonates without IVIG treatment in ABO hemolytic disease, such as ETCOc,total serum bilirubin level before IVIG treatment and ETCOc,total serum bilirubin level after IVIG treatment.To explore the clinical value of ETCOc in the treatment of ABO hemolytic disease.
Key facts
- Study ID
- NCT05842109
- Run by
- Women's Hospital School Of Medicine Zhejiang University
- People needed
- 112
- Starts
- 2023-10-31
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-02-05
Who can join
Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- gestational age between 35+0 and 41+6 weeks
- birth weight ≥ 2500 grams
- respiratory rate < 60 breaths per minute
- the neonates admitted to the neonatology department for phototherapy because of hyperbilirubinemia that conforms to the guideline of the experts consensus on the management of neonatal hyperbilirubinemia(2014,in China.)
- ABO group incompatibility between the mother and newborn
- the informed consent are obtained.
You may not qualify if…
- persistent dyspnea or need for respiratory support
- skin damage or structural deformity around the nasal cavity
- receive intensive care treatment in the neonatal intensive care unit(NICU)
- Severe congenital malformation, chromosomal or genetic abnormality
Where it is running
- Women's hospital School of medicine Zhejiang University — Hangzhou, China (enrolling)
Full record on ClinicalTrials.gov
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