The Stanford Egg Freezing Study

Completed · Not applicable

Conditions studied: Fertility Issues, Reproductive Issues

In brief

The purpose of this study is to see if the investigators can obtain non-inferior clinical outcomes (similar numbers of oocytes) using the Cardinal protocol, a cost-conscious, low-intensity egg freezing protocol, compared to other routinely used high-intensity clinic protocols. This is a new program for Stanford's Fertility Clinic, so the investigators are assessing patient experience and cost-benefit of a low-cost, low-intensity approach that has demonstrated non-inferiority in IVF for infertility treatment, but has not been similarly evaluated in egg freezing. All enrolled participants will choose the Cardinal protocol or the routine high-intensity protocol designated by their physician. The investigators will then assess number of eggs retrieved, as well as patient satisfaction, cost, and time needed off work to complete the egg freezing cycle. The study's findings could ultimately open the door to implementation of lower-cost standardized protocols that would be more affordable and accessible to people who may otherwise not be able to pursue fertility preservation.

Key facts

Study ID

NCT05842070

Run by

Stanford University

People needed

168

Starts

2023-07-26

Expected to finish

2025-04-04

Last updated by the study team

2026-01-20

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Ovary-bearing individuals of reproductive age 18-40, interested in pursuing OC
• AMH > 0.3 ng/mL
• AMH < 7 ng/mL

You may not qualify if…

• AMH > 7 ng/mL or physician concern for risk of developing severe OHSS
• History of severe OHSS
• Severe diminished ovarian reserve (DOR) def. as AMH < 0.3 ng/mL or FSH > 15
• BMI > 45
• Any contraindications to ovarian stimulation or outpatient egg retrieval under anesthesia

Where it is running

• Stanford Fertility and Reproductive Health Services — Sunnyvale, California, United States

Full record on ClinicalTrials.gov

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