Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia

Completed · Phase 3

Conditions studied: Schizophrenia

In brief

This study evaluates the efficacy of two prescription digital therapeutics (PDT) in addition to standard of care (SOC) therapy for the treatment of experiential negative symptoms of schizophrenia in late adolescents and adults.

Key facts

Study ID

NCT05838625

Run by

Click Therapeutics, Inc.

People needed

464

Starts

2023-03-31

Expected to finish

2025-07-23

Last updated by the study team

2026-06-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A participant will be eligible for entry into the study if all of the following criteria are met:
• Has a primary diagnosis of schizophrenia.
• Is on a stable dose of antipsychotic medication(s).
• Has obtained an average score of ≥2 (moderate to severe) in at least two of the three CAINS-MAP domains (Social, Work, or Recreational).

You may not qualify if…

• A participant will not be eligible for study entry if any of the following criteria are met:
• Is currently treated with more than two antipsychotic medications (including more than two dosage forms).
• Meets DSM-5, for diagnoses not under investigation.
• Has participated in a CT-155 clinical study.

Where it is running

• Investigational center — Phoenix, Arizona, United States
• Investigational center — Anaheim, California, United States
• Investigational center — Culver City, California, United States
• Investigational center — Garden Grove, California, United States
• Investigational center — La Habra, California, United States
• Investigational center — Long Beach, California, United States
• Investigational center — Los Angeles, California, United States
• Investigational center — Newport Beach, California, United States
• Investigational center — Oceanside, California, United States
• Investigational center — Orange, California, United States
• Investigational center — San Bernardino, California, United States
• Investigational center — Torrance, California, United States
• Investigational center — Cromwell, Connecticut, United States
• Investigational center — Hartford, Connecticut, United States
• Investigational center — Hialeah, Florida, United States
• Investigational center — Largo, Florida, United States
• Investigational center — Miami, Florida, United States
• Investigational center — Miami Lakes, Florida, United States
• Investigational center — Orlando, Florida, United States
• Investigational center — West Palm Beach, Florida, United States
• Investigational center — Atlanta, Georgia, United States
• Investigational center — Augusta, Georgia, United States
• Investigational center — Chicago, Illinois, United States
• Investigational center — Springfield, Illinois, United States
• Investigational center — Chandler, Arizona, United States

Full record on ClinicalTrials.gov

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