Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Recruiting now · Phase 4

Conditions studied: Dental Implant Failed, Peri-implant Mucositis, Peri-Implantitis

In brief

The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:

Key facts

Study ID

NCT05838365

Run by

University of Milan

People needed

220

Starts

2022-12-01

Expected to finish

2029-06-01

Last updated by the study team

2023-05-01

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Sistemically healthy patients
• partial edentulism
• premolar position
• molar position
• Bone width and height at least 6 and 10mm, respectively.
• Keratinized tissue, at least 1 mm at implant site
• Full understanding of the proposed surgical treatments and the protocol schedule
• Full comprehension and availability to sign the informed consent form

You may not qualify if…

• Heavy smokers (>10 cigarettes a day)
• Serious kidney or liver diseases
• Uncontrolled diabetes
• Bisphosphonates intake
• History of radiotherapy of the head and neck
• Current antiblastic chemotherapy
• Congenital (primary) or acquired (secondary) immunodeficiency
• Pregnant women
• Connective tissue disorders
• Local exclusion criteria:
• untreated stage III/IV periodontitis
• Autoimmune diseases
• oral parafunctions

Where it is running

• San Paolo Hospital — Milan, Italy (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.