InheriteD brEast caNcer iTalian regIsTrY A Retrospective-prospective Observational Cohort Study to Evaluate Cancer Prevention Strategies in Women With a Deleterious Mutation in BRCA1-2
Recruiting now
Conditions studied: Breast Cancer
In brief
The purpose of the study is to obtain and centralize data about cancer prevention strategies in women with a germline deleterious mutation in BRCA1-2 with or without a history of breast cancer in Italy
Key facts
- Study ID
- NCT05835739
- Run by
- Centro di Riferimento Oncologico - Aviano
- People needed
- 78
- Starts
- 2019-08-27
- Expected to finish
- 2035-09-30
- Last updated by the study team
- 2023-04-28
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Cohort A (Retrospective):
- Female sex
- Age ≥ 18 years
- Signed informed consent
- Documented germline deleterious mutation in BRCA1 and/or BRCA2 in people with: i) No history of cancer ii) Radically treated breast cancer iii) Stage IV breast cancer diagnosed after BRCA1-2 mutation detection
- Admission to the participating Center since 1st of January 2010, prior to site activation
- Cohort B (Prospective):
- Female sex
- Age ≥ 18 years
- Signed informed consent
- Documented germline deleterious mutation in BRCA1 and/or BRCA2 in people with: i) No history of cancer ii) Radically treated breast cancer iii) Stage IV breast cancer diagnosed after BRCA1-2 mutation detection
- Admission to the participating Center after site activation
You may not qualify if…
- Cohort A/B (Retrospective/Prospective):
- Other malignancies diagnosed within five years prior to BRCA1-2 mutation detection, except for:
- ovarian cancer stage I-II
- basal or squamous cell carcinoma of the skin
- melanoma in situ
- CIS of the cervix
Where it is running
- Centro di Riferimento Oncologico - Aviano — Aviano, Pordenone, Italy (enrolling)
- IRCCS AOU San Martino, IST Genova — Genova, Italy (enrolling)
- Azienda Ospedaliera Papardo — Messina, Italy (enrolling)
- ASST Ovest Milanese — Milan, Italy (enrolling)
- Azienda ospedaliera Universitaria di Modena — Modena, Italy (enrolling)
- Università degli studi di Napoli Federico II — Naples, Italy (enrolling)
- Azienda AUSL IRCCS - Reggio Emilia — Reggio Emilia, Italy (enrolling)
- ASL Roma 1, Santo Spirito — Roma, Italy (enrolling)
- IFO - Istituto Regina Elena (Oncologia medica 2) — Roma, Italy (enrolling)
- Policlinico Universitario Gemelli — Roma, Italy (enrolling)
- Città della salute Torino, PO S. Anna — Torino, Italy (enrolling)
- ASU FC Azienda Sanitaria Universitaria Friuli Centrale — Udine, Italy (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.