Metabolic Cost of Walking With Passive vs. Powered Prosthetic Knees Among Persons With Limb Loss

Recruiting now · Not applicable

Conditions studied: Transfemoral Amputation

In brief

The purpose of this industry-initiated research study is to test that a powered microprocessor controlled knee improves metabolic function during walking in level and sloped conditions as compared to the subject's physician prescribed prosthesis.

Key facts

Study ID

NCT05831696

Run by

Loma Linda University

People needed

12

Starts

2023-02-27

Expected to finish

2026-12-01

Last updated by the study team

2026-02-04

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and Females with unilateral knee disarticulation or transfemoral (KD/TF) amputation.
• a body mass greater than 49Kg and less than 117Kg
• 18-75 years of age
• Have an ambulation potential of K3 or K4
• Use a prosthesis daily for walking or sports activities
• No less than six months of experience with a prosthesis
• No socket issues or changes in the last six weeks
• No residual limb pain affecting functional ability.

You may not qualify if…

• Cannot walk at different speeds (MCFL K0-K2)
• Limb-loss below the knee or through the hip
• More than one amputation.
• Uses an assistive device for walking
• Uncontrolled edema in leg compartments
• Compromised skin of the residual limb or contralateral foot
• Are 180 days or less post-amputation
• Pregnant (self-reported)

Where it is running

• Loma Linda University — Loma Linda, California, United States (enrolling)

Full record on ClinicalTrials.gov

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