Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

Recruiting now · Not applicable

Conditions studied: Perineural, Methylene Blue, Lower Limb Amputation

In brief

This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role against chronic phantom pain in patients undergoing lower limb amputation surgery

Key facts

Study ID

NCT05830630

Run by

Tanta University

People needed

72

Starts

2023-05-01

Expected to finish

2027-11-01

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients of both genders, suffering from vascular insufficiency of one or both lower limbs and scheduled for above or below knee amputation under general anesthesia.

You may not qualify if…

• Patients with a history of allergy to local anesthetics.
• Patients with allergy to methylene blue.
• Anticoagulant use or coagulopathy.

Where it is running

• Tanta University — Tanta, Gharbia Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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