North American Prodromal Synucleinopathy Consortium Stage 2

Enrolling by invitation

Conditions studied: REM Sleep Behavior Disorder, Parkinson Disease, Lewy Body Dementia, Dementia With Lewy Bodies, Multiple System Atrophy, REM Sleep Parasomnias

In brief

This study will enroll participants with idiopathic REM sleep behavior disorder (RBD) and healthy controls for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.

Key facts

Study ID

NCT05826457

Run by

Washington University School of Medicine

People needed

500

Starts

2022-08-12

Expected to finish

2028-05-01

Last updated by the study team

2026-05-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

• University of California Los Angeles — Los Angeles, California, United States
• Stanford University — Redwood City, California, United States
• Emory University — Atlanta, Georgia, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Mayo Clinic Rochester — Rochester, Minnesota, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• Oregon Health Sciences University — Portland, Oregon, United States
• McGill University Health Centre Research Institute — Montreal, Quebec, Canada

Full record on ClinicalTrials.gov

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