The Clinical Course and Factors for the Progression of Uninvestigated Dyspepsia to Functional Dyspepsia
Recruiting now
Conditions studied: Dyspepsia
In brief
Dyspepsia is one of the most common gastrointestinal diseases. This disease was defined as predominant epigastric pain lasting for at least 1 month, which can be accompanied with other symptoms, such as epigastric fullness, and early satiety. Despite dyspepsia symptoms lasting for ≥1 month represented clinical problem, a longer duration of 6 months or more after first-onset symptom was required for the diagnosis of functional dyspepsia based on ROME IV criteria. It was unclear about the natural procession of first-onset dyspepsia to functional dyspepsia assessed by Rome IV or Asia criteria and possible factors associated with this progression.
Key facts
- Study ID
- NCT05823636
- Run by
- Air Force Military Medical University, China
- People needed
- 220
- Starts
- 2023-01-01
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2024-09-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged ≥ 18 years old who had first-onset dyspepsia with one or more symptoms of epigastric pain, epigastric burning, postprandial fullness, early satiation and that has lasted for more than 1 month to 3 months.
You may not qualify if…
- Patients with local or systemic diseases which may cause dyspeptic symptoms:
- Known active peptic ulcer, cholecystitis, gallstone, gastrointestinal obstruction, gastroparesis, and etc.
- Known acute or chronic injury of liver or kidney
- Obvious hematological abnormality, or endocrine and metabolic diseases
- Known malignancy; Obvious cardiovascular or cerebrovascular diseases (such as coronary heart disease, arrhythmia, cerebral infarction and etc.
- Other conditions which may be associated with dyspeptic symptoms (such as NSAIDs associated dyspepsia)
- organ failure defined by Marshall standard or severe psychiatric illnesses
- pregnancy or lactation
- unable to provide consent
Where it is running
- Air Force Military Medical University, China — Xi'an, Shaanxi, China (enrolling)
Full record on ClinicalTrials.gov
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