Investigating Neural Biomarkers for Gait in Parkinson's Patients

Recruiting now

Conditions studied: Parkinson Disease, Gait Disorders, Neurologic

In brief

This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options. Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.

Key facts

Study ID

NCT05820074

Run by

Swiss Federal Institute of Technology

People needed

60

Starts

2023-04-13

Expected to finish

2025-03-01

Last updated by the study team

2024-12-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• All participants
• must have given informed consent as documented by signature
• agree to comply with the study procedures
• Healthy control group
• no neurological, orthopedic, or rheumatologic disease history
• no identified sensory impairment.
• no epilepsy and self-diagnosed acute or chronic psychiatric disorders
• Parkinson's Patients
• non-tremor dominant idiopathic PD patients
• presence of postural instability (UPDRS >1 for postural instability [17]), gait disturbance, and absence of other causes of reduced balance
• Implanted with Percept™ PC neurostimulator
• Able to be in the stimulation OFF

You may not qualify if…

• Relevant cognitive impairment, with a score on Montréal Cognitive Assessment (MoCA) < 20
• History of physical or neurological condition that interferes with study procedures
• Social and/or personal circumstances interfering with the ability to come to the session

Where it is running

• Cereneo — Vitznau, Canton of Lucerne, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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