Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days

Stopped early · Early Phase 1

Conditions studied: Nausea, Pain

In brief

Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.

Key facts

Study ID

NCT05819619

Run by

Hackensack Meridian Health

People needed

8

Starts

2023-07-20

Expected to finish

2024-04-11

Last updated by the study team

2025-11-17

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Healthy
• English speaking
• female volunteers undergoing medical abortion whether for voluntary interruption of pregnancy or missed abortion
• Gestational age </= 70 days confirmed via ultrasound
• Access to a time keeping device
• Willingness to complete a telephone or in-clinic follow up

You may not qualify if…

• chronic medical problems including but not limited to cardiac conditions, malignancy or organ damage
• Failed medical abortion resulting in surgical management
• Known intrauterine infection
• Known allergy to ondansetron or ibuprofen
• Subjects chronically receiving analgesic drugs
• Subjects unable to give consent
• Subjects taking medications that interact with ondansetron or ibuprofen

Where it is running

• Antonia Oladipo — Hackensack, New Jersey, United States

Full record on ClinicalTrials.gov

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