Transcranial Direct Current Stimulation for Post-stroke Fatigue

Recruiting now · Phase 2 · Has a placebo group

Conditions studied: Fatigue, Stroke Rehabilitaion

In brief

The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke.

Key facts

Study ID: NCT05816603
Run by: Weill Medical College of Cornell University
People needed: 24
Starts: 2023-05-23
Expected to finish: 2027-12-01
Last updated by the study team: 2026-02-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Male or female patients aged >18 years
Greater than 3 months from first hemorrhagic or ischemic stroke (subacute to chronic), confirmed through neuroimaging (CT or MRI).
Fatigue severity score average >4 (severe fatigue)
Willingness to remain stable on pharmacologic therapy through the duration of the study.
Availability of a caregiver, family member, or friend to be present during the administration of the tDCS intervention.

You may not qualify if…

Metal in the head (except mouth) or implanted cranial or thoracic devices (i.e. pacemaker, DBS stimulator)
History of seizure
History of moderate to severe traumatic brain injury
A score of 10 or more on the PHQ-9 or GAD-7 scale, suggestive of moderate to severe depression/anxiety.
A score of less than 21 on the MoCA suggesting major neurocognitive disorder.
Signs of skin rash, infection, or laceration in the supraorbital region where the tDCS will be applied.
Inability to provide informed consent
Other major neurological, medical, or psychiatric illnesses that could confound results in the opinion of the site investigator.

Where it is running

Weill Cornell Medicine, 525 E. 68th St, Baker Pavilion, F-2106 — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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