NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health
Completed · Not applicable
Conditions studied: Pregnancy Related, Substance Use, Mental Health Issue
In brief
This exploratory study brings together an interprofessional team, novel tools, and innovative, community-driven care delivery approaches to improve health equity among mother-infant dyads impacted by substance use disorder and high risk for poor health outcomes. This study will test a community-informed and community-based intervention using a fetal ultrasound protocol, motivational interviewing techniques, strength-based education, and healthcare coordination strategies to reduce health disparities faced by women and their children.
Key facts
- Study ID
- NCT05814575
- Run by
- Virginia Commonwealth University
- People needed
- 103
- Starts
- 2023-06-08
- Expected to finish
- 2025-11-30
- Last updated by the study team
- 2026-08-05
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Pregnant persons, Aged 18 through 45, between 22-32 weeks gestation at study entry
- Provision of signed and dated informed consent form
- Not incarcerated
- Able to read and understand English
- For infants after delivery, parental informed consent to participate in the study
- Stated willingness to comply with all study procedures
- Meets Diagnostic and Statistical Manual 5 criteria for Substance Abuse or substance use disorder in the last 12 months or is in active treatment for substance use disorder (including Nicotine/Tobacco, alcohol, marijuana, illicit and licit substances, and opioids) or actively using substances during pregnancy.
- Willingness to participate in the NEXUS regimen
You may not qualify if…
- Presenting with cognitive impairment
- psychiatric instability (active psychosis or acute mania)
- language or legal barriers that would limit the patient's ability to provide informed consent and complete research assessments.
- Known fetal anomalies
- Medical conditions requiring frequent ultrasound monitoring outside the study (e.g.
- Gestational Diabetes)
Where it is running
- Virginia Commonwealth University — Richmond, Virginia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.