8.4% Sodium Bicarbonate Locks in Intestinal Failure
Completed · Phase 2
Conditions studied: Intestinal Failure, CRBSI - Catheter Related Bloodstream Infection
In brief
We plan to include children with intestinal failure, a condition where the gut is not functioning properly, leading these children to need central venous catheters (line that goes through the skin into the blood stream) for nutritional support and hydration. Such patients have a very high risk for catheter infection. The study will include placing an agent (sodium bicarbonate) into the central catheter when the catheter is not in use. This is referred to as a lock. The lock would be used daily and removed when patients start their nutritional support and hydration through the catheter.
Key facts
- Study ID
- NCT05813535
- Run by
- Riad Rahhal
- People needed
- 6
- Starts
- 2022-12-01
- Expected to finish
- 2025-03-01
- Last updated by the study team
- 2026-05-28
Who can join
Age: 1 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subject fulfills diagnosis of intestinal failure with a central venous catheter in place used daily on outpatient basis for intravenous nutrition and /or intravenous hydration
- Subject is less than 18 years of age at the time of study entry
- Subject with history of at least 1 documented catheter related blood stream infection (verified by blood culture)
Where it is running
- University of Iowa — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
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