Changes in Metabolic Rate and Perceptual Indicators After Acute Ingestion of Paraxanthine
Completed · Not applicable · Has a placebo group
Conditions studied: Metabolic Syndrome, Caffeine
In brief
The purpose of this study is to evaluate the acute impact of ingesting individual and combined dosages of caffeine and paraxanthine in comparison to placebo on changes in resting metabolic rate, perceived levels of affect, and markers of lipolysis.
Key facts
- Study ID
- NCT05811923
- Run by
- Lindenwood University
- People needed
- 20
- Starts
- 2021-12-12
- Expected to finish
- 2022-10-12
- Last updated by the study team
- 2023-04-13
Who can join
Age: 18 and older, up to 39. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- All participants will be between the ages of 18-39 years
- Participants will be healthy and free of disease as determined by evaluation of a - medical history
- All participants will be required to abstain from taking any additional forms of nutritional supplementation (pre-workouts, creatine, beta-alanine, thermogenic supplements, etc.) for four weeks prior to beginning this study and for the entire duration of the study
- Participant's report accumulating at least 30 minutes of moderate exercise 3 days per week
- Currently have a body mass index between 18.5 - 25 kg/m2. Alternatively, individuals with a body mass index between 25 - 30 kg/m2 will be included in the study if body-fat percentage is below 32% for females and 25% for males.
- Not currently restricting calories or completing a dieting program
- As determined through a caffeine intake survey, participants will be moderate caffeine consumers, consuming approximately 200 mg of caffeine per day.
You may not qualify if…
- Those individuals less than 18 and greater than 40 years of age will be excluded. Participants younger than 18 are excluded due to necessity of parental consent. Participants greater than 40 years old are excluded due to the known changes that occur with metabolic rate as individuals achieve an age of 40 years or greater
- As indicated on a self-reported medical history, any individual who is currently being treated for or diagnosed with a cardiac, respiratory, circulatory, musculoskeletal, metabolic, obesity (defined as body mass index > 30 kg/m2), immune, autoimmune, psychiatric, hematological, neurological, or endocrinological disorder or disease will be excluded.
- Regular (>3 days/week) administration of thermogenic supplements or other weight loss aids in the past 60 days
- Participants not meeting minimum exercise guidelines (30 minutes per day, 3 days per week) or exceeding 8 hours of exercise per week will be excluded
- Daily intake of caffeine doses exceeding 300 mg/day
- Participants who do not or are not willing to abstain from alcohol, nicotine, and caffeine for 12 hours prior to each visit will be excluded
- Participants who do not or are not willing to abstain from exercise for 24 hours prior to each visit will be excluded.
- Participants who do not or are not willing to follow the prescribed dietary control leading up to each exercise bout will be excluded
- Individuals who are pregnant, nursing, or trying to get pregnant
Where it is running
- Exercise and Performance Nutrition Laboratory — Saint Charles, Missouri, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.