Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

Recruiting now

Conditions studied: Neuropathic Pain

In brief

This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.

Key facts

Study ID

NCT05811312

Run by

VA Office of Research and Development

People needed

40

Starts

2023-07-01

Expected to finish

2027-06-30

Last updated by the study team

2026-06-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age and a US veteran
• Diagnosis of chronic neuropathic pain.
• Current patient at Cleveland VA Medical Center receiving care via Pain Medicine Center.
• Current user of tonic parasthesia-based SCS (pain relief 50% according to NPRS) or undergoing trial SCS period as part of clinical care.
• Able to provide informed consent.
• Medically and psychologically stable.

You may not qualify if…

• Metal in the skull or deformity of the skull
• Pregnancy or pregnancy planning during the study period.
• Unable to provide informed consent.

Where it is running

• Louis Stokes VA Medical Center, Cleveland, OH — Cleveland, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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