A Study to Assess the Accuracy of Magnetocardiography (MCG) to Diagnose True Ischemia in Patients With Chest Pain in the ED

Enrolling by invitation

Conditions studied: Chest Pain, Emergency Medicine

In brief

The purpose of the research is to see if patients that come to the Emergency Department with chest pain can be more accurately and more quickly diagnosed by magnetocardiography (MCG) to see if their chest pain is caused by coronary ischemia (reduced blood flow to the heart) in patients with normal or have non-specific changes on the ECG vs other causes by other reasons.

Key facts

Study ID

NCT05809648

Run by

Mayo Clinic

People needed

1000

Starts

2023-03-17

Expected to finish

2026-12-01

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients presenting to the ED with acute chest pain when an ACS is on the differential diagnosis.
• Patient willing and able to give informed consent.

You may not qualify if…

• ST elevation > 1 mm on any two contiguous ECG leads.
• Hemodynamic instability (SBP >220 or <80, HR >160).
• Pregnant patients.
• Incarcerated patients (FMC patients).
• Patients with a pacemaker or defibrillator.
• Metal implants in the body (that are not MRI safe).
• Patients that are unable to lie down in the MCG machine or stay still.
• Patients who are unable to understand the informed consent process (ex: non-English speakers without an available interpreter, cognitive delay).
• Patients without the capacity to provide written informed consent

Where it is running

• Mayo Clinic Minnesota — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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