ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery

Running, not enrolling · Not applicable · Has a placebo group

Conditions studied: Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use

In brief

This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound infiltration in reducing thyroid surgery postoperative pain. Primary outcomes assessed are post operative pain, quality of life/recovery, post operative nausea/vomiting and opioid use.

Key facts

Study ID

NCT05805423

Run by

University of California, Davis

People needed

74

Starts

2023-04-17

Expected to finish

2026-12-31

Last updated by the study team

2026-05-12

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• undergoing thyroid surgery, either hemi- or total thyroidectomy
• over 18 years-old and
• able to consent for themselves

You may not qualify if…

• have had previous neck surgery
• have coagulation disorders
• on anticoagulants
• are pregnant
• allergic to bupivacaine
• anyone with chronic pain conditions
• has received steroid injections or used opioids/pain medications in the two weeks leading up to surgery
• have a substernal goiters
• undergoing lateral neck lymph node dissection
• unable to take NSAIDs
• kidney dysfunction (defined as GFR <60) within 90 days of surgery, prohibiting the use of NSAIDs

Where it is running

• UC Davis Medical Center — Sacramento, California, United States

Full record on ClinicalTrials.gov

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