The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

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Conditions studied: Vascular Diseases

In brief

This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

Key facts

Study ID

NCT05802706

Run by

University Hospital of Limerick

People needed

300

Starts

2016-01-01

Expected to finish

2027-01-01

Last updated by the study team

2025-04-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
• Able to provide informed consent.

You may not qualify if…

• Patients that are unable to give informed consent.
• Seriously ill/unconscious patients.

Where it is running

• University Hospital Limerick — Limerick, Limerick, Ireland (enrolling)

Full record on ClinicalTrials.gov

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