Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression
Recruiting now
Conditions studied: Glaucoma
In brief
The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.
Key facts
- Study ID
- NCT05801471
- Run by
- Centervue SpA
- People needed
- 200
- Starts
- 2022-05-06
- Expected to finish
- 2028-11-06
- Last updated by the study team
- 2026-01-02
Who can join
Age: 40 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Glaucomatous optic nerve head in both eyes;
- Age between 40 and 90 years;
- Best Corrected Visual Acuity ≤ 0.3 [logMar];
- Spherical refraction between -6D and +6D;
- Astigmatism between -2D and +2D.
You may not qualify if…
- Any ocular surgery, except for: uncomplicated cataract surgery and/or glaucoma surgery in both eyes performed within 6 months before enrollment;
- Any ocular pathology that can affect visual field other than glaucoma;
- Use of any drug that can interfere with the correct execution of perimetry or that would produce visual field loss;
- Inability to obtain reliable perimetric examinations;
- Patients with advanced glaucoma for whom, according to the clinician, a 24-2 grid is not advisable to correctly monitor the patient.
Where it is running
- Clinica oculistica Ospedale San Paolo — Milan, Milano, Italy (enrolling)
- Glaucoma Research Center, IRCCS Fondazione "G.B. Bietti" — Roma, Roma, Italy (enrolling)
Full record on ClinicalTrials.gov
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