A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Recruiting now · Phase 1
Conditions studied: Advanced Prostate Cancer, Metastatic Prostate Cancer
In brief
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and preliminary activity of RO7656594 in participants with advanced or metastatic prostate cancer. It will also identify recommended doses and regimens for RO7656594 for subsequent studies.
Key facts
- Study ID
- NCT05800665
- Run by
- Genentech, Inc.
- People needed
- 210
- Starts
- 2023-05-02
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-07-10
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- HonorHealth — Scottsdale, Arizona, United States (enrolling)
- Yale Cancer Center — New Haven, Connecticut, United States (enrolling)
- Sarah Cannon Research Institute @ Florida Cancer — Orlando, Florida, United States (enrolling)
- University of Illinois Hospital & Health Sciences System — Chicago, Illinois, United States (enrolling)
- SCRI Oncology Partners — Nashville, Texas, United States (enrolling)
- St Vincent's Hospital Sydney — Darlinghurst, New South Wales, Australia (enrolling)
- Macquarie University Hospital — New South Wales, New South Wales, Australia (enrolling)
- Monash Health Monash Medical Centre — Clayton, Victoria, Australia (enrolling)
- Austin Hospital — Heidelberg, Victoria, Australia (enrolling)
- British Columbia Cancer Agency — Vancouver, British Columbia, Canada (enrolling)
- Princess Margaret Hospital — Toronto, Ontario, Canada (enrolling)
- Gustave Roussy — Villejuif, Val-de-Marne, France (enrolling)
- Centre Léon Bérard — Lyon, France (enrolling)
- Institut Paoli Calmettes — Marseille, France (enrolling)
- Seoul National University Hospital — Seoul, South Korea (enrolling)
- Severance Hospital Yonsei University Health System - PPDS — Seoul, South Korea (enrolling)
- Asan Medical Center - PPDS — Seoul, South Korea (enrolling)
- Samsung Medical Center - PPDS — Seoul, South Korea (enrolling)
- Clinica Universidad de Navarra — Pamplona, Navarre, Spain (enrolling)
- Hospital Universitario Vall d'Hebron - PPDS — Barcelona, Spain (enrolling)
- Clinica Universidad de Navarra-Madrid — Madrid, Spain (enrolling)
- Hospital Clinico San Carlos — Madrid, Spain (enrolling)
- Cambridge Clinical Research Centre — Cambridge, United Kingdom (enrolling)
- Leicester Royal Infirmary — Leicester, United Kingdom (enrolling)
- The Christie — Manchester, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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