Maternal Characteristics Associated With Child Growth and Adiposity

Recruiting now

Conditions studied: Obesity, Obesity, Infant

In brief

The goal of this observational study is to investigate the concentrations of leptin, insulin, liver expressed antimicrobial peptide 2 (LEAP2), and cortisol in plasma and breast milk and their relationship with eating behavior, growth, adiposity and with the levels of these hormones in infants, comparing mothers with normal weight and with pre-pregnancy overweight/obesity. The main question\[s\] it aims to answer are: * Are maternal hormones associated with child growth and adiposity * Are maternal hormone receptors associated with child growth and adiposity * Are infant hormones and their receptors associated with child growth and adiposity * Are maternal and infant hormones and their receptors associated with child eating behavior Participants will provide milk and blood samples. Researchers will compare mothers with normal weight and with pre-pregnancy overweight/obesity to see if there are differences in child growth and adiposity .

Key facts

Study ID

NCT05798676

Run by

Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri

People needed

130

Starts

2019-05-02

Expected to finish

2028-03-01

Last updated by the study team

2025-12-26

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Lactating women with pre-pregnancy normal weight and overweight or obesity as described by the World Health Organization.

You may not qualify if…

• Diabetes (Type I or II or gestational)
• Multiple pregnancy
• Hypertensive disorders during pregnancy
• Delivery of pre-term infant (<37 weeks).

Where it is running

• Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri — La Plata, Buenos Aires, Argentina (enrolling)

Full record on ClinicalTrials.gov

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