Maternal Stress and Blood Sugar Metabolization

Running, not enrolling

Conditions studied: Pregnancy

In brief

During pregnancy, gestational diabetes increases the risk of complications and adverse outcomes for mother and child, however about 50% of gestational diabetes cases are diagnosed without a known risk factor present. This project uses both a large sample retrospective study, and a prospective study to help us understand the mechanisms by which mental health and stress impact glucose metabolization during pregnancy and delineate their contribution to gestational diabetes and racial disparities. The investigators expect, to improve the ability to identify women at risk, and advance options for preventative care and treatment, decreasing the impact of gestational diabetes and related complications.

Key facts

Study ID

NCT05798377

Run by

Sanford Health

People needed

150

Starts

2023-05-31

Expected to finish

2027-01-31

Last updated by the study team

2026-03-20

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• At least 18 years old
• Less than 17 weeks
• Healthy single baby pregnancy

You may not qualify if…

• History of diabetes
• History of Gestational diabetes mellitus (GDM)
• History of cardiac disease
• History of endocrine disease
• Assistive reproductive technology (in-vitro fertilization)

Where it is running

• Sanford Health — Sioux Falls, South Dakota, United States

Full record on ClinicalTrials.gov

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