Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Recruiting now · Not applicable

Conditions studied: Distal Femur Fracture

In brief

Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence. Fixation of these fractures can be challenging due to altered anatomy for the TKA and the presence of the metallic femoral component and have a relatively high complication rate. As a result, some surgeons elect to treat these fractures with a distal femur replacement total knee arthroplasty (DFR). The purpose of this study is to prospectively evaluate periprosthetic femur fractures treated with ORIF or DFR and compare various outcomes measures (Get up and go times, KOOS Jr score)

Key facts

Study ID

NCT05792189

Run by

University of Florida

People needed

100

Starts

2023-04-12

Expected to finish

2029-04-01

Last updated by the study team

2025-07-31

Who can join

Age: 55 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English speaking patients
• 55 years or older with Su Type II or Su Type III periprosthetic femur fractures or OTA/OA 33C or 338/3 native knee distal femur fracturing requiring surgical intervention and are medically fit to undergo surgical intervention

You may not qualify if…

• Patients with an active total knee prosthetic infection
• Patients unable to undergo surgical intervention
• Patient with an open fracture
• Non-English-speaking patients
• Oncologic/pathologic fracture
• Poly-trauma patient (or other associated major orthopaedic injuries)

Where it is running

• UF & Shands Orthopaedics and Sports Medicine Institute — Gainesville, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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