Heart Failure Optimization at Home to Improve Outcomes (Hozho): A Pragmatic Clinical Trial in Navajo Nation
Completed · Not applicable
Conditions studied: Heart Failure
In brief
Heart failure causes significant morbidity and mortality, particularly in Navajo Nation. There are well-established evidence of improved mortality and lower heart failure hospitalizations with certain pharmacotherapies for heart failure with reduced ejection fraction (HFrEF). However, these medications are underutilized nationally, including in the Indian Health Service which is one important driver of poor heart failure outcomes. Therefore, as part of an EHR-based pragmatic clinic trial, we are implementing and testing a model that identifies American Indian HFrEF patients receiving care at one large Indian Health Service Site who meet clinical criteria for, but are not on appropriate therapy, and implements a model in patients are initiated and titrated on appropriate therapy over the phone with remote tele monitoring using home blood pressure cuff. We will evaluate the impact of this model to improve uptake of GDMT among HFrEF patients.
Key facts
- Study ID
- NCT05792085
- Run by
- University of Pennsylvania
- People needed
- 103
- Starts
- 2023-02-01
- Expected to finish
- 2023-08-01
- Last updated by the study team
- 2025-01-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with heart failure with reduced ejection fraction with last ejection fraction equal to or less than 40%
- Have a primary care physician at Gallup Indian Medical Center or Tohatchi Health Center
- Have been seen in the last 12 months at Gallup Indian Medical Center or Tohatchi Health Center
You may not qualify if…
- On hospice
- LVAD/translant
- Home inotropes
- No visit in last 12 months at Gallup Indian Medical Center or Tohatchi Health Center
Where it is running
- Gallup Indian Medical Center — Gallup, New Mexico, United States
- Tohatchi Health Center — Tohatchi, New Mexico, United States
Full record on ClinicalTrials.gov
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