Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by ECMO-VA for Refractory Cardiogenic Shock
Recruiting now
Conditions studied: Cardiac Rhythm Disorder
In brief
Brief Summary : Rhythm disorders are a frequent and potentially serious complication of critical patients in the ICU and postoperative cardiac surgery. In particular, atrial fibrillation (AF) is the most common rhythm disorder in patients admitted to the ICU and is associated with excess mortality during acute circulatory failure. In postoperative cardiac surgery, AF affects 15 to 45% of patients. In addition to hemodynamic effects, AF increases the risk of stroke, bleeding, respiratory or renal failure, and doubles mortality at 30 days and 6 months. In the longer term, the recurrence rate of AF within 1 year after hospital discharge is about 50%. Similarly, other rhythm disorders, supraventricular or ventricular, can be life-threatening in ICU patients. While the incidence and complications of rhythm disorders are well documented during sepsis, cardiogenic shock or after cardiac surgery, there are to our knowledge no data on the frequency and complications of rhythm disorders in patients assisted by VA ECMO. The primary objective is to describe the incidence of supraventricular rhythm disorders in patients assisted by VA ECMO.
Key facts
- Study ID
- NCT05788120
- Run by
- Assistance Publique - Hôpitaux de Paris
- People needed
- 600
- Starts
- 2023-04-28
- Expected to finish
- 2028-04-28
- Last updated by the study team
- 2026-04-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient 18 years of age or older
- Assistance with VA ECMO
You may not qualify if…
- Opposition to the use of data.
- Persons under legal protection (curators, guardianship), judicially safeguarded.
- VA ECMO for refractory cardiac arrest.
Where it is running
- CHRU Nancy - Hôpitaux de Brabois — Vandœuvre-lès-Nancy, France (enrolling)
- Hospices Civils de Lyon - Hôpital Louis Pradel — Bron, France (enrolling)
- CHU Caen Normandie - Hôpital Côte de Nacre — Caen, France (enrolling)
- CHU Rennes, Hôpital Pontchaillou — Rennes, France (enrolling)
- CHU Toulouse - Hôpital de Rangueil — Toulouse, France (enrolling)
- CHU Toulouse - Hôpital de Rangueil — Toulouse, France (enrolling)
- CHU Angers — Angers, France (enrolling)
- CHU Dijon Bourgogne - Hôpital François Mitterrand — Dijon, France (enrolling)
- CHU Grenoble Alpes - Site Nord — Grenoble, France (enrolling)
- CHU Montpellier - Hôpital Arnaud de Villeneuve — Montpellier, France (enrolling)
- CHU Nantes - Hôpital Nord Laennec — Nantes, France (enrolling)
- Pitié Salpêtrière Hospital, Intensive Care Unit - Resuscitation — Paris, France (enrolling)
- Pitié-Salpêtrière Hospital, Cardiovascular Surgery Intensive Care Unit — Paris, France (enrolling)
- Hôpital Européen Georges Pompidou — Paris, France (enrolling)
- Hôpital Bichat — Paris, France (enrolling)
- Hôpital Bichat — Paris, France (enrolling)
- CHRU Tours - Hôpital Trousseau — Chambray-lès-Tours, France
- Hôpitaux universitaires de Strasbourg - Hôpital Civil — Strasbourg, France
- CHU Bordeaux - Hôpital cardiologique, GH Sud Pessac — Pessac, France
- CHU Lille - Institut Cœur Poumon — Lille, France
Full record on ClinicalTrials.gov
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